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VCD Spectroscopy

Methods IPH, Müller

VCD Spectroscopy Model: Bruker Tensor 27 IR spectrometer with PMA 50 VCD Module (MCT Detector)
Unit and Room: Pharmaceutical Chemistry, 02.043/047
Responsible: Dr. Steffen Lüdeke
Spectroscopy Further information:  

Short Description:

FTIR spectrometer with VCD side bench including ZnSe photo elastic modulator and lock-in amplifier.

Picture of the Equipment

VCD Spectroscopy
 

Available Experiments/Techniques:

Vibrational circular dichroism on solids, neat liquids and solution samples.
Instrument can also be used as stand alone FTIR in transmission and diamond ATR experiments. 

Special Equipment:

150 µL volume KBr cells for standard non-aqueous measurements. 20 µL volume BaF2/CaF2 cells on request.

Measurements on the equipment are currently done by: Students after extensive training
Trained scientific service personal
 
Recent Publications, where this instrument was
important (citation):
Adv. Synth. Catal. 2009, 351, 253-259.
 
Typical problems that may be solved with this instrument: - determination of absolute configuration in combination with quantum chemical prediction of VCD spectra
- elucidation of secondary structure of peptides and proteins
- estimation of enatiomeric excess
- detection of supramolecular chirality 

 

pdficon.gif VCD Spectroscopy (this page as a pdf file)

 

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