Supercritical CO2 Reactor

Methods IOC, Bannwarth

Supercritical CO₂ Reactor (sc CO₂ Reactor)	Model:	Autoclave Engeneers
	Unit and Room:	Org. Chemistry, 2nd floor, R. 323F
	Responsible:	Prof. W. Bannwarth
Synthesis	Further information:
Short Description: High-pressure stainless-steel reactor equipped with a mechanical stirrer, a thermocouple, an internal manometer, and a sapphire window. The reactor possesses an inlet valve fitted with a 6-port HPLC valve for the addition of liquid substrates and an outlet valve for CO₂.		Picture of the Equipment
Available Experiments/Techniques: Solvent properties can be varied via pressure and cosolvents to have a detailed influence on the speed and selectivity of catalytic reactions. Simple work up, nearly solvent-free products, especially useful for thermic instable compounds or pharmaceutics.
Special Equipment: Pickel's Original Supercritical Fluid Chromatography
Measurements on the equipment are currently done by:		Students after intensive training
Recent Publications, where this instrument was important (citation):		C.C. Tzschucke, C. Markert, W. Bannwarth, S. Roller, A. Hebel, R. Haag; Angew. Chem. 2002, 114, 4136-4173 N. Bruns, W. Bannwarth, J. C. Tiller, Biotechnology and Bioengineering, 2008, 101, 19 - 26
Typical problems that may be solved with this instrument:		-extraction of natural products -can be used as an environment-friendly and nontoxic medium -high solubility of organic fluorous compounds in sc CO₂