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Peptide Synthesizer

Methods IOC, Bannwarth

Peptide Synthesizer Model: Peptide Synthesizer SP 4000-LAB
Labortec AG
Unit and Room: Org. Chemistry, 1st floor, R. 221F
Responsible: Prof. W. Bannwarth, S. Mundinger
Synthesis
Further information:  
Short Description:

Semi-automated instrument for the solid
phase synthesis of peptides.

Picture of the Equipment

Peptide Synthesizer
 

Available Experiments/Techniques:

Solid phase synthesis of peptides via BOC-
and Fmoc synthesis methods on a scale of
0.2-5mMol. (Solvents and reagents are fed by
gravity using special Boyle-Mariotte bottles).

Incorporation of N-a-amino acids into a
peptide of any desired sequence with one end
of the sequence remaining attached to a solid
support matrix.

Special Equipment:

2 different synthesis reactors for the built-in shaker (50 and 100 ml capacity)

Measurements on the equipment are currently done by:

Students after Introduction
Trained scientific service personal 

Recent Publications, where this instrument was
important (citation):

E.K. Kainmüller, W. Bannwarth; Helv. Chim.
Acta, 2006, 89, 3056-3070

Typical problems that may be solved with this instrument:

Synthesis of modified and non modified
DNA-strands. Synthesis of DNA/RNA
hybrids.

 

pdficon.gif Peptide Synthesizer (this page as pdf file)

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