DNA Synthesizer

The Expedite™ 8909 Nucleic Acid Synthesis
System is an economical, versatile platform
that synthesizes DNA and RNA
oligonucleotides with fast cycle times and a
low cost-per-base ratio. The system is ideal
for synthesizing short primers and probes as
well as sequences up to 100-mers in scales
ranging from 50 nmol to 15 µmol. The basic
Expedite 8909 system features independently
controlled, simultaneous dual-column
synthesis.

The DNA synthesis is performed using ß-
cyanoethyl phosphoramidite chemistry. Since
the synthesizer has 9 positions for the
insertion of phosphoramidites it is possible to
synthesize DNA/RNA hybrids. Furthermore
modified nucleotides can be inserted and
directly coupled during the automated
synthesis.

Special Equipment:

Diod Array Detector
Multi-System Interface
Remote Control

Students after Introduction
Trained scientific service personal 

D. Altevogt, A. Hrenn, C. Kern, L. Clima, W.
Bannwarth, I. Merfort, Org. Biomol. Chem. ,
2009, 7, 3934 - 3939
L. Clima, W. Bannwarth, Helv. Chim. Acta,
2008, 91, 165-175

Synthesis of modified and non modified
DNA-strands. Synthesis of DNA/RNA
hybrids.