Differential Scanning Calorimetry
Methods IBC, Einsle/Friedrich/Andrade
| Differential Scanning Calorimetry | Model: | GE Healthcare / Microcal VP-DSC capillary scanning calorimeter |
| Unit and Room: | Biochemistry, 9th floor, R.910 | |
| Responsible: | Dr. Stefan Gerhardt | |
| Thermal Analysis, Calorimetry | Further information: | http://portal.uni-freiburg.de/xray/equipment |
| Short Description: The VP-Cap DSC is an autosampling differential scanning microcalorimeter. The reference and sample cells are fixed in place capillary shaped vessels with effective volumes of approximately 130 µl. The cells are constructed from a tantalum alloy and protrude out of the adiabatic chamber via their two 1.5 mm (inner diameter) access tubes. The approximate volume of each pair of cell stems is 120 µL. | Picture of the Equipment
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| Available Experiments/Techniques: The VP-Cap DSC operates in the temperature range of -10° to 130° C and is capable of scanning with no external heating/cooling source. Scanrates are user selectable and fall in the range of 0°/hr to +250°/hr. . | ||
Special Equipment: | ||
| Measurements on the equipment are currently done by: | Students after extensive training | |
| Recent Publications, where this instrument was important (citation): | BMC Biochemistry 8:13.
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| Typical problems that may be solved with this instrument: | - Thermal stability of a sample, in particular folding and unfolding events in proteins. | |
Differential Scanning Calorimetry (this page as pdf file)